Report on effectiveness of NDV treatments

en español
Statistics compiled by Kind Hearts In Action between December 2008 and March 2014.

“I’m sorry, but your dog has distemper. You should have him put to sleep.”

This is what dog owners around the world are told far too often. According to the experts, distemper is an incurable disease from which few dogs survive. Euthanasia is the frequent course of action.

But we’d like to show you some facts that we hope will give the experts a reason to think again. Hundreds, perhaps thousands, of dogs could be needlessly dying of this disease every year.

Since December 2008, Save Dogs From Canine Distemper, a project of Kind Hearts In Action, has been tracking the effectiveness of a treatment discovered by a veterinarian in Lancaster, California. Dr. Alson Sears could not get the veterinary community to listen to him when he first discovered NDV-induced serum in the late 1960s. But now, our numbers support – if not yet prove – Dr. Sears’ claim that distemper is curable.

We do not claim here that we have proven this cure, but we consider these treatments to be at least encouraging and worth further investigation.

We have received reports from 21 vets who have used NDV to treat distemper dogs. Of those, 12 vets used NDV-induced serum in the early stages of the disease, and in 86 percent of those cases, the distemper dog survived. Dog caregivers — owners, fosters and rescuers — tell us that 63.39 percent of distemper dogs were saved by one of the treatments developed by Dr. Sears using NDV — Newcastle Disease Vaccine.

These numbers were compiled from e-mails from dog caregivers and from a survey of vets using the NDV treatments. These statistics support our primary conclusion that if dogs can be treated within four to six days of the onset of symptoms, the majority of these animals can be saved. Our conclusion is also supported by a study conducted in Korea in 2003, which is included below. However, the survival rate also relies on getting a fast diagnosis, on having a supply of serum available, and in successfully treating the dog for the opportunistic diseases — such as pneumonia — that usually accompanies distemper.

History

Dr. Alson Sears, a veterinarian in the desert community of Lancaster, Calif., discovered how to use Newcastle Disease Vaccine (NDV) as a treatment for canine distemper in the early 1970s . The basic principle of the treatment is to use the NDV as an inducer to prompt a reaction in the dog’s immune system that can create a material to kill the distemper virus. The protocol for making the serum is available here.

Dr. Sears reports treating more than 600 dogs for canine distemper during his years as a practicing vet. He says that dogs infected with the distemper virus treated before going through the sixth day of showing symptoms had a survival rate in the high 90s. Dr. Sears was not able to get his discovery published. He retired in 2006.

However, his treatment had been made available on the Internet since May 2000 [http://www.edbond.com/distemper.html], and some vets have followed his treatments and theories with success. Today, the NDV treatments include the NDV-induced serum, the NDV as an IV injection to the body and the NDV spinal tap, which is for dogs in the neurologic stage of distemper.

With a treatment that had been discovered in the early 1970s and available on the Internet for more than 13 years, the question has often been raised about why more conclusive information has not been published before now.

This is because:

  1. After his discovery, Dr. Sears ran into overwhelming disbelief about his treatments. “Son, that’s impossible. Sit down,” he was told when he tried to explain his discovery at a veterinary conference. This was a discouraging experience for him.
  2. He lacked the resources and ability to get his work published. When he contacted major universities about his discovery, he was told he would have to pay $500,000 to have a research project conducted. As a simple, clinical vet trying to meet the expenses of running his clinic, he had no way of paying so much. So, he remained quiet about his discovery for decades.
  3. While his treatments were posted on a website in May 2000, the Save Dogs From Distemper project did not get started until December 2008. We have compiled these preliminary statistics on cases treated since then in the hope that this may be useful to researchers.

How this report was compiled

The data for the report comes from two sources:

  1. Veterinarians using NDV
  2. Dog owners, caregivers or rescue groups.

Every case reported to us has been included in our statistics. We are not selective in compiling our information.

Kind Hearts In Action contacted veterinarians using NDV with either a mailed survey, through the Internet and e-mail and sometimes by phone. They were asked:

  • Do you use NDV to treat canine distemper?
  • Do you use NDV serum?
  • How many dogs have you treated with NDV serum?
  • How many of those dogs survived?
  • Do you use NDV in an IV?
  • How many dogs have you treated with NDV in IV?
  • How many of those dogs survived?
  • Have you used the NDV spinal tap?
  • How many dogs have you treated with the NDV spinal tap?
  • How many of those dogs survived?

For this survey, the diagnosis of distemper relied on the judgment of each vet. Very often, the dog owners did not want to pay the additional expense of a lab test. So, the vets would make the diagnosis based on their experience, the apparent symptoms and in the context of whether they were in the midst of a distemper outbreak. The reports from owners and dog caregivers was largely tracked by e-mail.

Because the means of diagnosis is inconsistent, we do not claim that these numbers prove canine distemper can be cured. Our work to prove the effectiveness of these treatments is not done. But we gathered these numbers as an attempt to give a sample of what is happening around the world. We hardly think that all distemper cases are being reported to us, and very often we are told that the cases we do know of are just a handful of examples out of a population where dogs are dying in overwhelming numbers.

Very often, much of the resistance about Dr. Sears’ theories comes from the conclusion that vaccination alone has the problem of distemper under control. While vaccination is essential to fighting this disease and we strongly encourage all dogs to be vaccinated, the numbers of cases that have been reported to us show that distemper is still a problem. Shelter outbreaks, exposure from wild animals and unvaccinated puppies allow the disease to continue.

It would be useful if a U.S. or international agency took on the role of compiling reliable statistics on how many dogs are dying of distemper. The veterinary community may not even fully realize how big the problem of distemper is.

Still, we feel these numbers at least show that there is hope. If this treatment can be published and accepted in a veterinary journal, we believe the lives of countless dogs can be saved.

Any vets who have information about dogs they have treated with NDV-induced serum are asked to e-mail Ed Bond at ed.bond.new.york@gmail.com. These statistics will be updated routinely as we receive further reports.

Report on outcomes from veterinarians

According to 21 veterinarians who have reported outcomes to Kind Hearts In Action, 532 dogs infected with the distemper virus have been treated with at least one of the NDV treatments. Of those, 372 survived (70 percent). Twelve of these vets reported treating 227 cases with the NDV-induced serum of which 196 survived, for a survival rate of 86 percent.

It is important to note that 150 of these dogs were treated in 2010 with NDV-induced serum by a Houston area vet as part of Project Hope. They report that of the 150 dogs that were treated with NDV-induced serum, 90 percent survived – 135 dogs. Combining these numbers with the efforts of other vets, Project Hope reports saving nearly 200 dogs from canine distemper.

The other cases include 162 dogs that were treated with NDV as an IV injection, of which 111 survived and 143 treated with NDV spinal taps of which 65 survived. Two of the surviving dogs treated with NDV as IV in Puerto Rico were also treated with NDV-induced serum.

Here is a report on a dog treated with the NDV spinal tap by a vet in Alberta, Canada.

In one of the spinal tap cases, a vet in South Africa injected the NDV-induced serum in the spinal canal — instead of the straight NDV vaccine — and that dog was reported to be doing well.

Vets who had reported on the effectiveness of the treatments were from Florida, Texas, California, Virginia, Puerto Rico, Canada, Turkey, Hungary, Romania, Italy, Mexico, South Africa and the Philippines. One vet in the Los Angeles area reported treating five dogs with NDV as IV, but did not learn the outcomes of those cases. Another vet in Southern Florida reports having used NDV on distemper dogs 27 times since 2009, but did not have the reports on outcomes available. These cases where the outcomes were unknown have not been added to the totals from the vets.

Report from Korea

A study on the effectiveness of the NDV-induced serum was also conducted in Korea in 2003. According to Dr. Kim Hee-Young, DVM, MS, PhD, the senior researcher for the Korea Animal Blood Bank, that was when he discovered the website about Dr. Sears’ treatment. He reports:

“In 2003, 102 dogs (from 12 vets) were diagnosed by ELISA as Distemper infection. Of them, the 54 dogs (52 %) were recovered completely on the check-up 6 weeks after the Sears treatment. In Korea, the success rate of conventional treatment in cases confirmed as Distemper (ELISA) was usually lower than 8 %.”

Dr. Sears’ serum has been available on the inventory of the Korea Animal Blood Bank since 2004.
 [http://board-1.blueweb.co.kr/board.cgi?id=vet20&bname=news&unum=14&action=view]

Dr. Kim Hee-Young writes:

“We have used Sears plasma (serum) in Distemper cases and found it works wonderful. … But, cases more than 5 days after symptoms or with neurological symptoms did not show any improvements. Some of the vets reported deterioration after injection. Thus, we don’t recommend to use it in cases which had shown distemper symptoms more than 4 days.”

Report on outcomes from dog caregivers

Since December 2008, dog caregivers — owners, fosters and rescuers — have reported the outcomes of 864 distemper cases to the Save Dogs From Distemper project. Of these, 571 dogs with distemper were treated with an NDV treatment and 362 survived (63.39 percent survival rate).

This includes:

  • 189 of 249 distemper dogs treated with serum that survived (76 percent).
  • 78 of 113 distemper dogs treated with NDV as an IV injection that survived (69 percent)
  • 95 of 209 dogs with neurologic distemper treated with the NDV spinal tap that survived. (45.5 percent)

There were also 293 cases that were not treated with NDV, of which 69 survived. (23.5 percent.) Also, 64 cases initially thought to be distemper were later diagnosed with a different disease. Of these, 51 dogs lived and 13 died. These were not included in the 852 cases listed above.

On Nov. 8, 2011, a dog owner from Monterrey, Mexico, reported that her puppy died shortly after being treated with NDV-induced serum. She wrote that before the NDV-serum treatment, another vet had also treated the puppy with a variety of treatments including Zylexis. After the death, the vet told the owner, “It was a shock MAYBE because of the serum mixed with the Zylexis.” Zylexis, which is used to boost the immune system of horses, is not part of Dr. Sears’ protocols.

Additional photos, videos and owner testimonials of dogs successfully treated for canine distemper are available at http://kindheartsinaction.com/

If you have additional reports to share with us, please e-mail ed.bond.new.york@gmail.com and we will update these numbers as we receive them.

Conclusions

If anything, the numbers above show that distemper can be a treatable and survivable disease. Even without using NDV, about 23 percent of dogs can survive the initial infection of distemper. However, those dogs that do survive without treatment often have done so through the extraordinary efforts of the owner or caregiver. Such dogs often survive with neurologic problems, damage to teeth, organs and other issues. But these dogs are also at risk to continuing and advancing neurologic problems that may lead to death later on.

The timely use of NDV can greatly increase the odds of survival and limit the damaging effects of the distemper virus. According to caregivers, the overall survival rate for dogs treated with one of the NDV treatments is 63.39 percent. According to vets, the overall survival rate is 70 percent, but that climbs to 86 percent when considering only those cases treated with the NDV serum before the onset of neural problems.

Our position continues to be that treating with the NDV serum before the dog goes through the sixth day of symptoms is the most advantageous way of treating distemper. The report from Korea recommends treating within four days of symptoms, and that also seems to be a reasonable goal. The sooner a dog can be treated, the better.

As to why these treatments work, our theory is that the NDV causes a reaction within a dog’s immune system that produces a previously unknown material or group of interacting materials, that is able to neutralize the invading virus. However, finding the answer would require extensive scientific research.

The IV injection of NDV does exist as an option for treating distemper if the NDV-induced serum is not available. The NDV vaccine can be acquired and given to a sick dog as an IV injection very quickly. So, many dogs have been saved that way, and it spares the dog owner from an agonizing delay as they would have to persuade a vet to make the NDV-induced serum with a donor dog.

However, the problem with giving the sick dog a straight injection of the NDV is that recovery relies on the animal’s immune system being strong enough to create the needed response to fight the distemper virus.

NDV as an IV injection may save a dog or puppy:

  • If the immune system is intact.
  • If it is older than 12 weeks.
  • If it is not a pure breed known to not have a response to NDV. This should not be the primary way to treat dogs, but might be used if the NDV-induced serum is not available.

If the dog’s immune system is strong enough, this material can be made from the NDV injection and save the animal. If the immune system is too damaged to respond or if the dog is of a breed that does not make the needed response, the straight NDV IV injection will not save the dog.

According to Dr. Sears, breeds that do not have the needed response to NDV include:

  • German shepherds
  • poodles
  • Irish setters
  • Gordon setters
  • English bulldogs
  • Shar Peis.

For puppies younger than 12 weeks, the best option to save them is to use the NDV-induced serum before the neurologic stage of the disease.

It has been with vets who already have the serum on hand that the most success has been seen. The timely diagnosis of distemper in dogs is also critical in saving lives. This is why Dr. Sears came up with a quick and reliable test for distemper by checking the cells of the bladder in what is called a Brush Border Smear.

Dr. Sears was able to save dogs at a rate in the high 90s because he was able to quickly identify distemper cases and treat the dogs before the narrow window of opportunity closed. Similarly, the vet in Houston was able to save a large majority of dogs because of the ability to treat dogs quickly with a readily available source of serum.

However, the use of the serum does not guarantee that a dog will be saved. Distemper often opens up other opportunistic infections such as pneumonia. Vets and caregivers have reported that even though they saw distemper symptoms reverse after NDV treatment, the dog died of pneumonia, another disease or medical problem. Dr. Sears has written a protocol of recommended treatments to give dogs an improved chance of survival.

As to the NDV spinal tap, it does offer some hope for the owner of a distemper dog that has gone into the neurologic stage of the disease. However, the chances of survival are less than 50 percent. For some of these dogs with neurologic distemper, they were saved because the caregivers put in extraordinary effort and intensive nursing care in addition to the NDV spinal tap. So, it exists as a way that can save some dogs. Here are some additional notes from Dr. Sears on measures to take after the NDV spinal tap.

Further information is available at http://kindheartsinaction.com/

We invite any reasonable, skeptical inquiries into this report.

Ed Bond
ed.bond.new.york@gmail.com
Kind Hearts In Action
March 18, 2014

Copyright © 2014 Kind Hearts In Action Corporation. All Rights Reserved.

Comments

  1. Teresa Martinez says:

    My dog “Harpie” was one of those that survived the spinal tap NDV from the Houston vet in December 2010. Within 3 days of receiving treatment her mucus was gone, eyes were clear, full puppy appetite, and full of energy. This serum works. I am very thankful that Kind Hearts in action pointed me in the right direction.

  2. mi cachorrito tiene el virus de distemper,y en mi pais no existe el trataniento del cual ustedes hablan,como podria adquirirlo

  3. I WANT TO GET THE MEDICINE THAT,IS USED AGAINST THE VIRUS DISTEMPER,

  4. pls..where can i buy ndv vaccine..my dog is 5 months…i live in puerto rico

  5. Where Can I Get This Medicine? My Puppy Caanot Walk Only On One Leg So Its Getting Worse.

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